Molecular characterization, comparative genome analysis and resistance determinants of three clinical <i>Elizabethkingia miricola</i> strains isolated from Michigan.

ABSTRACT:

Introduction

Elizabethkingia miricola is a gram-negative bacterium that causes life-threatening infections in vulnerable populations. Unlike other species in the Elizabethkingia genus, E. miricola also leads to meningitis-like diseases in aquatic invertebrates such as frogs, raising concerns about its zoonotic transmission potential. Management of its infection is complicated by unclear transmission pathways and multi-drug resistance.

Methods

In this study, we analyzed three clinical strains (E. miricola Mich-1, Mich-2, and Mich-3) isolated from patients in Michigan using morphology observations, biochemical tests, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF/MS), and genome sequencing.

Results

Ave

SUBMITTER: Chen S 

PROVIDER: S-EPMC12283610 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature