Association between periodontal disease and Alzheimer's disease: umbrella review.

ABSTRACT:

Background

Alzheimer's disease (AD) and periodontal disease (PD) are both chronic conditions with rising global prevalence. Emerging research suggests a possible link between PD-induced systemic inflammation and neurodegeneration observed in AD.

Objective

Employ an umbrella review to look into the association between periodontal disease and Alzheimer's disease.

Materials and methods

A comprehensive search was conducted until March 2025 across various electronic databases, including: PubMed, Cochrane Library, Scopus, SciELO, Web of Science, Google Scholar, ProQuest, and OpenGrey, and Dissertations and Theses. There were no time or language restrictions on the inclusion of systematic reviews (SR), with or without meta-analysis, as long as they looked at primary research

SUBMITTER: Arbildo-Vega HI 

PROVIDER: S-EPMC12283705 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature