Bleeding prediction scores in patients with venous thromboembolism using direct oral anticoagulants.

ABSTRACT: We aimed to identify factors associated with bleeding in patients with venous thromboembolism (VTE) when using direct oral anticoagulants (DOACs), to construct and externally validate a predictive model for bleeding, and to provide a validated tool for clinical assessment of bleeding. The prediction model in the development cohort was constructed using logistic regression and visualized through a Nomogram. We conducted external validation of the model. The accuracy and calibration were evaluated through the area under the curve (AUC), calibration curves, and the Hosmer-Lemeshow test. This multicenter retrospective study recruited 1121 patients treated with DOACs for VTE. The training set consisted of 806 patients from 11 centers and the external validation set consisted of 315 patients fro

SUBMITTER: Wu G 

PROVIDER: S-EPMC12283757 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature