Prostate motion in magnetic resonance imaging-guided radiotherapy and its impact on margins.

ABSTRACT:

Purpose

This study focused on reducing the margin for prostate cancer treatment using magnetic resonance imaging-guided radiotherapy by investigating the intrafractional motion of the prostate and different motion-mitigation strategies.

Methods

We retrospectively analyzed intrafractional prostate motion in 77 patients with low- to intermediate-risk prostate cancer treated with five fractions of 7.25 Gy on a 1.5 T magnetic resonance linear accelerator. Systematic drift motion was observed and described by an intrafractional motion model. The planning target volume (PTV) margin was calculated in a cohort of 77 patients and prospectively evaluated for geometric coverage in a separate cohort of 24 patients.

Results

The intrafractional model showed that the prostate positi

SUBMITTER: Kusters J 

PROVIDER: S-EPMC12283804 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature