Association of salivary proteins with dental caries in children with mixed dentition: a systematic review.

ABSTRACT:

Purpose

To review the current evidence on the association between salivary protein profile and dental caries in children during mixed dentition stage.

Methods

This systematic review followed the PRISMA 2020 guidelines. Searches were run in PubMed, Scopus and Embase along with gray literature. The searches were limited to studies on humans, published from inception to February 2024. Observational studies exploring correlations between salivary proteins and caries in children during mixed dentition (6-13 years) were included. The methodological quality of included studies was analyzed independently by two reviewers using the Joanna Briggs checklist and Newcastle-Ottawa scale, respectively followed by a qualitative synthesis.

Results

A total of 17 primary studies were in

SUBMITTER: Raja M 

PROVIDER: S-EPMC12283824 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature