Epidemiologic trends for pediatric Hodgkin and non-Hodgkin lymphomas: a U.S. population-based study.

ABSTRACT: Pediatric Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) are distinct from adult forms and occur less frequently. We identified 7,871 children and 226,211 adults with lymphoma from the Surveillance, Epidemiology, and End Results database from 1975 to 2018. The age-adjusted incidence rate for pediatric lymphoma was 24.5 per million persons (95% CI: 24.0-25.1), comprising 13.0 per million (95% CI: 12.6-13.4) for HL and 11.5 per million (95% CI: 11.1-11.9) for NHL. In comparison to adult lymphoma, pediatric lymphoma showed no significant changes in incidence from 1975 to 2002 (annual percentage change, APC = -0.12 ± 0.19, P = 0.53), but displayed an observable increase after 2003 (APC = + 1.31 ± 0.45, P = 0.006). Among pediatric cases, the 5-year limited-duration prevalence rate increas

SUBMITTER: Cheng W 

PROVIDER: S-EPMC12283834 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature