Novel prognostic impact and cell specific role of endocan in patients with coronary artery disease.

ABSTRACT:

Background

Both the clinical and mechanistic impacts of endocan were not well elucidated especially in coronary artery disease (CAD).

Objective

This study aimed to investigate the prognostic and potential pathological role of endocan for cardiovascular (CV) events in stable CAD patients.

Methods

A total of 1,071 stable CAD patients with previous percutaneous coronary intervention (PCI) were enrolled prospectively in a nationwide Biosignature study. Another cohort of 76 CAD patients with or without PCI were enrolled for validation. Baseline biomarkers including endocan level was measured and total CV events especially hard CV events (including CV mortality, non-fatal myocardial infection and stroke) during follow-up were identified. Circulating endothelial progenitor c

SUBMITTER: Lin LY 

PROVIDER: S-EPMC12283892 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature