Menstrual cycle characteristics across the reproductive lifespan and cognitive function in midlife women.

ABSTRACT:

Background

Menstrual cycle characteristics are potential indicators of hormonal exposures and may also signal cardiovascular disease risk factors, both of which are relevant to cognitive health. However, there is scarce epidemiological evidence on the association between cycle characteristics and cognitive function.

Objective

We studied the associations of menstrual cycle characteristics at 3 stages of a woman's reproductive lifespan with cognitive function in midlife.

Study design

We studied participants from the Nurses' Health Study II, an ongoing longitudinal cohort of female nurses initially enrolled in 1989. Exposures were cycle regularity at 14 to 17 and 18 to 22 years, and cycle length (the interval between 2 consecutive cycles) at 18 to 22 years (all retrospec

SUBMITTER: Soria-Contreras DC 

PROVIDER: S-EPMC12284091 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature