Type 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort.

ABSTRACT:

Background

The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly after its identification in December 2019 to cause a global pandemic. The respiratory tract is the primary site of infection, and there is a large range in the severity of respiratory illnesses caused by the virus. Defining molecular and cellular factors for protection from severe disease and death has been a goal to better understand and to predict and mitigate the effects of SARS-CoV-2 and future coronaviruses.

Objective

Despite well-known susceptibilities to respiratory viral infections, respiratory allergy and allergic asthma have not been identified as risk factors for severe coronavirus disease 2019 (COVID-19) in most epidemiologic studies and may be protective.

SUBMITTER: Jayavelu ND 

PROVIDER: S-EPMC12284355 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature