EASL postgraduate course report: Vascular biology in chronic liver disease and clinical management implications.

ABSTRACT: This article reviews the content of the EASL Congress 2024 postgraduate course on vascular biology in chronic liver disease and its clinical management. It focuses on haemostasis in patients with cirrhosis, vascular liver diseases including porto-sinusoidal vascular disorder and portal vein thrombosis, and portal hypertension and its extrahepatic complications in cirrhosis. Haemostatic changes in cirrhosis coincide with complex shifts between the risks of bleeding and thrombosis, making management decisions challenging. Importantly, laboratory test abnormalities should not be routinely corrected to avoid bleeding. Regarding vascular liver diseases, the term porto-sinusoidal vascular disorder is a recently redefined entity encompassing various overlapping histological patterns (e.g.

SUBMITTER: Rautou PE 

PROVIDER: S-EPMC12284368 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature