Dissemination of extended-spectrum beta-lactamase-producing <i>Escherichia coli</i> in poultry in Zimbabwe.

ABSTRACT: Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli are resistant to the critically important third- and fourth-generation cephalosporin antibiotics and present a risk to animal and human health. In Zimbabwe, there is an evidence gap concerning the prevalence and diversity of ESBL-producing E. coli in poultry. In this study, we screened for ESBL-E. coli at farms (n=50) and markets (n=10) using MacConkey agar supplemented with 4 µg ml^-1 ceftriaxone. ESBL-E. coli were detected at every market and at 21 farms, giving a farm-level prevalence of 42%. Seventy isolates were obtained and tested for antimicrobial susceptibility, whilst 69 of these were further analysed by whole-genome sequencing. A total of eight distinct bla

SUBMITTER: Katsande P 

PROVIDER: S-EPMC12284406 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature