Capture of Group A <i>Streptococcus</i> by open-microfluidic CandyCollect device in pediatric patients.

ABSTRACT:

State the purpose

Obtaining high-quality samples to diagnose streptococcal pharyngitis in pediatric patients is challenging due to discomfort associated with traditional pharyngeal swabs. This may cause reluctance to go to the clinic, inaccurate diagnosis, or inappropriate treatment for children with sore throats. Here, we determined the efficacy of CandyCollect, a lollipop-inspired open-microfluidic pathogen collection device, to capture Group A Streptococcus (GAS) and compare user preference for CandyCollect, conventional pharyngeal swabs, or mouth swabs in children with pharyngitis and their caregivers.

Results

All child participants (30/30) were positive for GAS by qPCR on both the mouth swab and CandyCollect. Caregivers ranked CandyCollect as a good sampling meth

SUBMITTER: Tu WC 

PROVIDER: S-EPMC12284423 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature