Design of a 3D-printing fluorescence detector for HPLC separation: a prototype device.

ABSTRACT: Herein, we developed a three-dimensional (3D)-printing fluorescence detector that could be connected to the HPLC system, and distinguished by its ease of assembly, cost-effectiveness, and high adaptability. The detector comprises a laser diode, a 3D-printing flow cell, quartz glass, a long-pass filter, a silicon phototube, and a voltmeter. Technically, the flow cell we designed here has a very compact structure, and it is convenient to embed the optical filter and the phototube, which is also a highlight of our detector to ensure the miniaturization of the whole device. Through the optimization of the detector's structural configuration, the adjustment of the various dimensions and relative positions of the detection window, and the removal of the metal encapsulation cover of the silicon p

SUBMITTER: Wu X 

PROVIDER: S-EPMC12284874 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature