Vip3C proteins from <i>Paenibacillus</i> spp. for controlling lepidopteran crop pests.

ABSTRACT: New proteins are needed to control insects not controlled with Bacillus thuringiensis (Bt) crops, and those evolving resistance to Bt crops. These proteins are increasingly being reported from non-Bt organisms to control Bt-resistant insects. However, these proteins mostly control the corn rootworm, Diabrotica spp. (Coleoptera), whereas most Bt-resistant insects are lepidopteran. We hypothesized that diversifying our search for proteins into non-Bt organisms, such as those related to Paenibacillus popilliae, used to control Japanese beetle Popillia japonica, could yield proteins with new insecticidal activities against Lepidoptera. Here, we identified Vip3Cb1 and Vip3Cc1 with broad lepidopteran activity, the first Vip3 proteins discovered from strains in the

SUBMITTER: Ciche T 

PROVIDER: S-EPMC12285222 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature