Comparison of Two Types of 1-L Polyethylene Glycol-ascorbic Acid as Colonoscopic Bowel Preparation: A Prospective Randomized Study.

ABSTRACT:

Background/aims

Recently, 1-L polyethylene glycol-ascorbic acid (PEG-Asc) has been used to reduce the volume of preparation agents in colonoscopy. This clinical trial aimed to compare the efficacy and safety of two types of 1-L PEG-Asc (CleanViewAL^® [Tae Joon Pharmaceutical Company, Seoul, Korea] and Plenvu^® [Norgine, Harefield, United Kingdom]) in average-aged adults.

Methods

This study was a prospective, randomized, non-inferiority, open-label, phase 4 clinical trial. The primary endpoint was the efficacy evaluated using the Boston bowel preparation scale (BBPS), and the secondary endpoint was clinical safety.

Results

In total, 173 patients were assigned to either the CleanViewAL^® (n=84) or Plenvu^® (n=89) group. Overall cl

SUBMITTER: Choi SH 

PROVIDER: S-EPMC12285351 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature