Genetic foundations of interindividual neurophysiological variability.

ABSTRACT: Neurophysiological brain activity shapes cognitive functions and individual traits. Here, we investigated the extent to which individual neurophysiological properties are genetically determined and how these adult traits align with cortical gene expression patterns across development. Using task-free magnetoencephalography in monozygotic and dizygotic twins, as well as unrelated individuals, we found that neurophysiological traits were significantly more similar between monozygotic twins, indicating a genetic influence, although individual-specific variability remained predominant. These heritable brain dynamics were mainly associated with genes involved in neurotransmission, expressed along a topographical gradient that mirrors psychological functions, including attention, planning, and e

SUBMITTER: da Silva Castanheira J 

PROVIDER: S-EPMC12285703 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature