Clinical Features of Hepatitis C Virus-related Acute-on-chronic Liver Failure in a Korean Population.

ABSTRACT:

Background/aims

Acute-on-chronic liver failure (ACLF) is a widely recognized concept in which acute decompensation (AD) in patients with cirrhosis results in organ failure and high short-term mortality. On the other hand, few studies reflecting the various etiologies of cirrhosis are available. This study examined the clinical features of patients with hepatitis C virus (HCV)-related ACLF.

Methods

Between January 2005 and December 2018, 109 HCV-related cirrhosis patients hospitalized for AD (ascites, hepatic encephalopathy, gastrointestinal hemorrhage, and bacterial infection) were enrolled for ACLF defined by the European Association for the Study of the Liver (EASL).

Results

ACLF developed in 35 patients (32.1%) on admission. Eight, eight, and 19 patients had ACLF g

SUBMITTER: Choi JW 

PROVIDER: S-EPMC12286097 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature