Contributions of different host species to the natural transmission of severe fever with thrombocytopenia syndrome virus in China.

ABSTRACT: Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne emerging infectious disease with a reported mortality rate of up to 30% in hospitalized patients. The causative agent, SFTS virus (SFTSV) is maintained in nature through a transmission cycle involving animal hosts and ticks. Therefore, effective control of SFTS in nature environments necessitates a comprehensive understanding of the tick-host circulation patterns that sustain viral persistence. We developed and calibrated mathematical models using seroprevalence survey data collected across China to assess the relative contributions of diverse domestic and wildlife host species to transmission, their determinants, and the effectiveness of various interventions. Our analysis identified poultry, previously unrecognized, as th

SUBMITTER: Cheng Q 

PROVIDER: S-EPMC12286343 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature