Preoperative Prediction of Microvascular Invasion in Intrahepatic Cholangiocarcinoma and Its Prognostic Implications: A Multicenter Study.

ABSTRACT:

Introduction

Previous studies on preoperative predictors of microvascular invasion (MVI) in intrahepatic cholangiocarcinoma (ICCA) have presented inconsistent results. This study aimed to identify preoperative clinical and magnetic resonance imaging (MRI) factors that can predict MVI in ICCA and to evaluate their prognostic utility using a multicenter cohort.

Methods

A multicenter cohort of 446 patients who underwent preoperative MRI and surgical resection for ICCA at six tertiary referral institutions between 2009 and 2018 was analyzed for clinical, pathologic, and MR imaging characteristics. Univariable and multivariable logistic regression analyses were performed to identify significant predictors of pathologically confirmed MVI, which were subsequently used to stratify p

SUBMITTER: Jang HJ 

PROVIDER: S-EPMC12286615 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature