Genetic Biomarkers for Periodontal Diseases: A Systematic Review.

ABSTRACT:

Aims

To identify genetic biomarkers that may be used in the diagnosis, prevention or management of different forms of periodontal disease.

Materials and methods

Following protocol registration and PICOTS (patient, intervention, comparison, outcome, time, studies) questions, a systematic search of the literature was conducted (PudMed, Ovid), resulting in 1592 papers screened by two reviewers. Diagnostic data were extracted or calculated from included papers and compared with clinically determined diagnoses, disease progression and/or response to treatment.

Results

A total of 607 articles met the inclusion criteria, including 10 reporting data on gingivitis and 597 on periodontitis. Only two papers reported diagnostic performance data, while for 41 articles on large can

SUBMITTER: Dommisch H 

PROVIDER: S-EPMC12286649 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature