Ultrasound radiomics models improve preoperative diagnosis and reduce unnecessary biopsies in indeterminate thyroid nodules.

ABSTRACT:

Purpose

Cytologically indeterminate thyroid nodules constitute 20-30% of fine-needle aspiration samples obtained from suspicious thyroid nodules. Over half of patients with indeterminate thyroid nodules undergo diagnostic surgery; however, 60-80% of excised nodules are benign. While some radiomics studies have built models to enhance the diagnostic efficacy of thyroid nodules, few have focused on indeterminate thyroid nodules with confirmed pathological results. We aimed to develop and evaluate ultrasound radiomics models to improve the diagnosis of indeterminate thyroid nodules and reduce unnecessary surgeries.

Methods

We retrospectively analyzed ultrasound images of 197 indeterminate thyroid nodules with definitive pathological results. Regions of interest were manually de

SUBMITTER: Chen L 

PROVIDER: S-EPMC12286800 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature