Phylogenetic analysis and genetic evolution of porcine respiratory coronavirus in Guangxi province, Southern China from 2022 to 2024.

ABSTRACT: Porcine respiratory coronavirus (PRCV) is an important coronavirus to cause respiratory syndrome in pigs. To analyze the genetic and evolutional characteristics of PRCV in Guangxi province, southern China, a total of 6,267 clinical samples were collected from different pig farms, harmless treatment plants and abattoirs in Guangxi province during 2022-2024. Seventeen positive samples of PRCV were selected to amplify and analyze the S, M, and N gene sequences. The results showed that the positivity rate of PRCV was 1.13% (71/6,267) using RT-qPCR. The homology analysis revealed that the nucleotide (amino acid) identity were 98.2-100% (96.6-100%) among the obtained 17 S, M, and N gene sequences, and 91.3-98.1% (88.8-98.0%) among the obtained strains and the reference strains from different cou

SUBMITTER: Shi Y 

PROVIDER: S-EPMC12287051 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature