Traction-assisted endoscopic submucosal resection (TA-ESD) for rectal neuroendocrine tumors: a randomized multi-center trial.

ABSTRACT:

Background and aim

Endoscopic resection is the first-line choice for the treatment of rectal neuroendocrine tumors (NETs). This study aimed to compare the efficacy and safety of a modified traction-assisted endoscopic submucosal resection (TA-ESD) and traditional endoscopic submucosal resection (ESD).

Methods

In this multi-center prospective randomized controlled trial, patients with small rectal NET(< 2 cm) were 1:1 randomized into TA-ESD or traditional ESD groups. The operation time was selected as the primary endpoint, while en bloc resection rate, R0 resection rate, complications, length of hospitalization were chosen as secondary endpoints.

Results

A total of 44 patients (22 TA-ESD and 22 ESD patients) were enrolled in this study, of which 40 patients (19 TA-ESD

SUBMITTER: Wu S 

PROVIDER: S-EPMC12287171 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature