Comparable efficacy of autogenous tooth-derived grafts and xenografts in post-extraction osseous defects: a split-mouth randomized trial.

ABSTRACT:

Objective

To evaluate the efficacy of autogenous tooth substitute graft (ATSG) prepared from autogenous third molars compared to xenograft in reducing osseous defects at the distal aspect of the second molars after impacted mandibular third molars removal.

Materials and methods

A randomized, double-blind, split-mouth clinical trial was conducted with 14 patients (aged 20-30 years) with bilateral mesioangular or horizontal impacted mandibular third molars. Following extraction, one socket received autogenous tooth-derived graft material (experimental site) prepared using a dentine grinder while the contralateral socket received xenogenic bone substitute (control site). Clinical parameters (probing depth, mobility, pain score, healing) and radiographic outcomes (mean gray valu

SUBMITTER: Laiamnuay P 

PROVIDER: S-EPMC12287208 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature