Comparative evaluation of fresh and lyophilized Nile tilapia fish skin for enhancing wound healing in a donkey model.

ABSTRACT: Recent advancements in wound care have explored the use of biological dressings, including fish skin, due to its rich collagen content and bioactive components that promote healing. This study aimed to evaluate the effectiveness of fresh and lyophilized Nile tilapia skin in enhancing full thickness skin wound healing in donkeys. Nile tilapia skin was collected, thoroughly washed, lyophilized, and sterilized. Five female donkeys were used in the study, each receiving three full-thickness skin wounds (2 cm x 2 cm) on each side of the back after aseptic preparation and local anesthesia, resulting in a total of six wounds per animal. The wounds were assigned to three groups: control (treated with saline), fresh fish skin, and lyophilized fish skin. Macroscopic wound assessment was performed an

SUBMITTER: Hussein KH 

PROVIDER: S-EPMC12287218 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature