The associations of calf circumference and cardiovascular and all-cause mortality among population with chronic kidney disease stages 3-5.

ABSTRACT: Previous studies have described the association between calf circumference (CC) and chronic kidney disease (CKD). We aim to evaluate the associations between CC and cardiovascular and all-cause mortality in patients with CKD stages 3-5. Data on CKD were sourced from the National Health and Nutritional Examination Survey (NHANES) 1999-2004. The population was stratified into three groups based on their CC tertile. Kaplan-Meier method with log-rank tests for significance was used for survival analysis. Weighted Cox proportional hazards regression models were employed to estimate the hazard ratios (HRs) for cardiovascular and all-cause mortality. The potential nonlinear relationship between CC and mortality was assessed using restricted cubic spline (RCS) models. Subgroup and sensitivity anal

SUBMITTER: Liu P 

PROVIDER: S-EPMC12287252 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature