Study of antibacterial activity of copper zinc nanocomposites and disruption of bacterial cytoplasmic membrane.

ABSTRACT: In recent years, the widespread use of antibiotics has led to the emergence of numerous drug-resistant bacteria, posing a severe threat to both human health and the economy. As a result, it is imperative to develop efficient antibacterial agents that do not induce drug resistance. This study employed layer-by-layer assembly technology to prepare ZnFe₂O₄@ZnS/Cu₂S (ZZC) nanocomposites Gram-negative Escherichia coli (E. coli), Gram-positive Staphylococcus aureus (S. aureus) and drug-resistant Salmonella (T-Salmonella) were utilized as test bacteria to investigate the antibacterial effectiveness and mechanism of ZZC. The findings demonstrated that, the MIC of the ZZC against E. coli, S. aureus and T-Salmonella were 50, 60 and 80 μg/mL, respectively; At a materi

SUBMITTER: Guo Z 

PROVIDER: S-EPMC12287259 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature