BZR1 promotes pluripotency acquisition and callus development through direct regulation of ARF7 and ARF19.

ABSTRACT: Plants have the remarkable ability to regenerate whole organisms through the formation of pluripotent cell masses from somatic cells. Cellular programs leading to fate change resemble lateral root (LR) formation and are chiefly regulated by auxin. Brassinosteroid signaling also plays an important role in LR formation, but little is known about the direct link between auxin and brassinosteroid components, such as BZR1 and BES1, in pluripotency acquisition. Here we show that gain-of-function mutants bzr1-D and bes1-D exhibit altered callus formation, yet disruption of these transcription factors does not cause major changes to callus formation or de novo organogenesis. Moreover, our data reveal that BZR1 displays enhanced expression in callus tissue and directly binds to the promoters of ARF

SUBMITTER: Ammitsoe T 

PROVIDER: S-EPMC12287390 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature