Clinical short-term analysis and effectiveness evaluation of optimally designed customized artificial talus implants.

ABSTRACT: Avascular necrosis (AVN) of the talus is a rare but debilitating condition that can lead to joint collapse and significant functional impairment. In advanced stages, joint-preserving surgical options are limited. This study aimed to develop a lightweight, patient-specific 3D-printed total talar implant and evaluate short-term clinical and radiographic outcomes in patients with idiopathic talar necrosis. A total of eight patients were approved for inclusion in this prospective clinical trial under the rare-disease framework established by the Ministry of Food and Drug Safety (MFDS) of Republic of Korea. Six patients underwent total talar arthroplasty starting in July 2023. As of this interim analysis, three patients had completed both the 6-week and 3-month postoperative follow-up assessmen

SUBMITTER: Kang Y 

PROVIDER: S-EPMC12287517 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature