Effect of continuous positive airway pressure on blood pressure in normotensive individuals with obstructive sleep apnoea: a randomised trial.

ABSTRACT:

Background

The effects of continuous positive airway pressure (CPAP) on blood pressure (BP) in normotensive subjects, particularly among those with a dipping BP pattern, remain uncertain, raising questions about its indication for this group of patients. We assessed the impact of CPAP on BP in normotensive subjects with a dipping BP pattern and severe obstructive sleep apnoea (OSA).

Methods

This was a randomised, parallel, prospective, controlled trial. Inclusion criteria were: age ≥18 years, apnoea-hypopnoea index ≥30 events·h^-1, mean 24-h BP <130/80 mmHg and daytime to night-time BP reduction ≥10%. Patients were randomly assigned to receive either CPAP treatment or usual care for 12 weeks. The primary outcome was the change in ambulatory BP monitoring (ABPM) par

SUBMITTER: Targa ADS 

PROVIDER: S-EPMC12287608 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature