Prognostic value of lipid parameters among patients with heart failure: A systematic review and meta-analysis.

ABSTRACT:

Aims

We sought to evaluate the prognostic value of different lipid parameters in patients with heart failure (HF).

Methods and results

Electronic databases including MEDLINE, Embase, CENTRAL, and Web of Science were searched to identify studies that reported the association of any of the four lipid parameters [total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides] with mortality among patients with HF. A random-effects model was used to estimate the association per 10 mg/dL increment. The QUIPS tool was used to assess the risk of bias. Fifty-two studies enrolling 93 286 patients were included. On univariable analysis, higher levels of the four lipid parameters were associated with lower mortality:

SUBMITTER: Sayed A 

PROVIDER: S-EPMC12287811 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature