In-hospital and 1 year incremental prognostic value of drug abuse detection in acute heart failure.

ABSTRACT:

Aims

The study aims to assess the in-hospital and 1 year incremental prognostic value of recent drug abuse use, detected by a systematic urinary screening, in a consecutive cohort of patients hospitalized for acute heart failure (AHF).

Methods

All patients admitted for AHF with a drug abuse screening using a urinary assay were included in this prospective multicentric study (39 French centres). The outcomes were (i) in-hospital major adverse cardiovascular events (MACEs) defined as all-cause death, resuscitated cardiac arrest or cardiogenic shock; and (ii) 1 year MACEs defined as cardiovascular death or hospitalization for AHF. Incremental prognostic value was assessed using the C-index, the global χ² and likelihood-ratio (LR) test, the net reclassification improv

SUBMITTER: Fauvel C 

PROVIDER: S-EPMC12287816 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature