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Clinical characteristics and long-term outcomes in patients with apical hypertrophic cardiomyopathy.


ABSTRACT:

Aims

As a special type of hypertrophic cardiomyopathy (HCM), apical HCM (ApHCM) has different clinical characteristics while its nature history and prognosis are not well recognized. We aimed to describe the characteristics and outcomes of ApHCM and identify predictors of adverse outcomes.

Methods

In this single-centre retrospective study, we included 479 patients with HCM and divided them into ApHCM and non-ApHCM groups. Clinical, electrocardiographic, echocardiographic and survival data were compared between the groups. The primary outcome was major adverse cardiac events in hospital and during follow-up. A two-sided P-value < 0.05 was considered statistically significant.

Results

A total of 109 ApHCM patients and 370 non-ApHCM patients were analysed and 379 patient

SUBMITTER: Guo M 

PROVIDER: S-EPMC12287849 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature