Plasma volume status predicting clinical outcomes in patients undergoing transcatheter edge-to-edge mitral valve repair.

ABSTRACT:

Aims

Plasma volume status (PVS) is recognized as a marker of systemic congestion, but its clinical utility in patients with mitral regurgitation (MR) undergoing transcatheter edge-to-edge mitral valve repair (M-TEER) has not been well established. This study aimed to evaluate the prognostic significance of PVS in these patients.

Methods and results

Data from 3763 patients who underwent M-TEER were analysed from a Japanese multicentre registry. Patients were classified into functional MR (FMR) and degenerative MR (DMR) according to MR aetiology, and the median PVS values for each were calculated (FMR 12.7, DMR 14.4). The median value was used as the cut-off, stratifying the cohort into a high PVS group (n = 1882) and a low PVS group (n = 1881). All-cause mortality, cardiovasc

SUBMITTER: Kagase A 

PROVIDER: S-EPMC12287850 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature