Higher Prescribed Opioid Use Among Adults With Crohn's Disease Than General Population: A Nationwide Cohort Study in Sweden 2006-2021.

ABSTRACT:

Background and aims

Population-based data on prescribed opioid use among adults with Crohn's disease (CD) remain limited.

Methods

This nationwide register-based study included individuals ≥ 18 years with incident (2008-2019) or prevalent (2008-2021) CD and up to 10 individually matched reference individuals without inflammatory bowel disease. We categorised opioid dispensations as weak (e.g., tramadol) or strong (e.g., oxycodone). We calculated the prevalence of ≥ 1 dispensation and mean daily doses (MDD) of opioids per 6 month period from 2 years before until 5 years following CD diagnosis (for incident cohort) and annual dispensation and MDD of opioids (for prevalent cohort).

Results

Among 10,527 patients with incident CD and 96,123 references, opioid dispensations

SUBMITTER: Osooli M 

PROVIDER: S-EPMC12287883 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature