Efficacy of probiotics pretreatment in <i>Helicobacter pylori</i> eradication therapy: a systematic review and meta-analysis of clinical outcomes.

ABSTRACT:

Background

Probiotics inhibit Helicobacter pylori (H. pylori) growth and alter gut microbiome, in addition to alleviating the side effects of H. pylori eradication. It has also been reported that H. pylori be eradicated after fecal microbiota transplantation in some cases. However, whether probiotics used before H. pylori eradication improves the eradication rate remains unclear. This study evaluates their role through a systematic review and meta-analysis.

Methods

We searched PubMed, EMBASE, the Cochrane Library, and the Conference Proceedings Citation Index up to January 31, 2024, to identify randomized controlled studies (RCTs) assessing the efficacy of probiotics used before H. pylori eradication. Meta-analyses of eradication rates were

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12288164 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature