Multi-objective CFD optimization of an intermediate diffuser stage for PediaFlow pediatric ventricular assist device.

ABSTRACT:

Background

Computational fluid dynamics (CFD) has become an essential design tool for ventricular assist devices (VADs), where the goal of maximizing performance often conflicts with biocompatibility. This tradeoff becomes even more pronounced in pediatric applications due to the stringent size constraints imposed by the smaller patient population. This study presents an automated CFD-driven shape optimization of a new intermediate diffuser stage for the PediaFlow pediatric VAD, positioned immediately downstream of the impeller to improve pressure recovery.

Methods

We adopted a multi-objective optimization approach to maximize pressure recovery while minimizing hemolysis. The proposed diffuser stage was isolated from the rest of the flow domain, enabling efficient evaluation

SUBMITTER: Zhussupbekov M 

PROVIDER: S-EPMC12288659 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature