Novel High-Throughput Electrochemical Detection of Staphylococcus Aureus, Bacillus Cereus, or Micrococcus Luteus Using AuNPs@Ti₃C₂T_z Functionalized with Sandwich Peptides.

ABSTRACT: Affinity-based electrochemical biosensors hold promise for detecting pathogenic bacteria in environmental applications. This study focuses on detecting gram-positive bacteria, which can cause fatal infections and are a major global mortality factor. An electrochemical biosensor platform using high-throughput 16-channel gold disk electrodes (16-GDEs) inspired by bio-microelectromechanical systems (BioMEMS) is developed, it incorporates a nanocomposite (AuNPs@Ti₃C₂T_z) with sandwich peptide structures to enhance electroconductivity and biological antifouling. Using AuNPs@Ti₃C₂T_z-coated 16-GDEs, sensitive biosensors for gram-positive bacteria (Staphylococcus aureus, Bacillus cereus, or Micrococcus luteus) are constructed and val

SUBMITTER: Park J 

PROVIDER: S-EPMC12288790 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature