Prenatal polycyclic aromatic hydrocarbon exposure and neurodevelopment among children in Puerto Rico.

ABSTRACT: Polycyclic aromatic hydrocarbons (PAHs) are widespread environmental contaminants produced through the combustion of organic matter, with sources ranging from traffic pollution to diet. Although PAH exposure has been associated with adverse health effects, few studies have examined its impact on neurodevelopmental delay (NDD). Thus, our study aims to investigate the effect of prenatal PAH exposure on the odds of NDD. We measured 7 hydroxylated PAH metabolites in spot urine samples collected up to three times during pregnancy in the PROTECT birth cohort. NDD was identified using score cutoffs from the Ages and Stages Questionnaire, 3rd edition offered in Spanish, across five domains at 12, 24, 36, and 48 months. We utilized logistic regression and mixed effects logistic regression models to

SUBMITTER: Sturla Irizarry SM 

PROVIDER: S-EPMC12289116 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature