Invasive Fungal Disease in Solid Organ and Hematopoietic Cell Transplant Recipients, United States.

ABSTRACT:

Background

Updated benchmark data on invasive fungal disease (IFD) in solid organ transplantation (SOT) and hematopoietic cell transplantation (HCT) recipients are necessary to increase clinical recognition and inform treatment and prevention strategies. We estimated IFD incidence and potential risk factors in transplant recipients in a large US commercial health insurance database.

Methods

We observed patients who received SOT or HCT during 2018-2022 until IFD development, disenrollment, or database end date (July 31, 2023). We calculated incidence (per 1000 person-years) and time to IFD development, comparing demographic features and underlying conditions for IFD versus non-IFD patients.

Results

Overall, 9143 patients received an SOT (5667 kidney, 2025 liver, 759 he

SUBMITTER: Gold JAW 

PROVIDER: S-EPMC12289323 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature