Metabolomic profiles impacted by brief mindfulness intervention with contributions to improved health.

ABSTRACT: Mounting evidence indicates that mindfulness-based interventions improve physical and mental health. However, whether brief mindfulness intervention supports health benefits by regulating metabolic profiles is poorly understood. To address this gap, this randomized controlled trial compared ten 1-hour sessions of integrative body-mind training (IBMT) with relaxation training (RT) in 42 participants. Untargeted metabolomics was performed on fasting serum samples to investigate the physiological effects of the interventions on metabolic profiles. After IBMT, significant increases were observed in glycine derivatives, glutamate, and tetrahexosylceramide, while multiple sulfur containing compounds decreased. In contrast, RT yielded no significant intervention effects. A direct comparison betwe

SUBMITTER: Tang YY 

PROVIDER: S-EPMC12290024 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature