Insights into physicochemical properties, stability in various aqueous media, and antibacterial activity of gallium-containing amorphous calcium phosphates.

ABSTRACT: Amorphous calcium phosphate (ACP) is a metastable phase that spontaneously crystallizes upon contact with aqueous media. Furthermore, modification of ACP with metal ions to confer specific biological functions may affect its stability. Crystallization of ACP is accompanied by physicochemical changes, which affect its biological properties. In this study, ACP powders with Ga content up to 2.2 ± 0.2 wt% were synthesized using a modified wet precipitation method. The synthesized powders' phase composition, functional groups, and morphology were analyzed. Overall, adding up to 2.2 ± 0.2 wt% of Ga had a negligible effect on the ACP physicochemical properties. The Ga-containing ACP (GaACP) stability was evaluated in deionized H₂O, phosphate buffer solution (PBS), Dulbecco's modified E

SUBMITTER: Vasiljevs R 

PROVIDER: S-EPMC12290073 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature