Risk of incident gout in rheumatoid arthritis from a nationwide cohort study in South Korea.

ABSTRACT: Rheumatoid arthritis (RA) coexisting with gout is considered rare, with only few case studies reporting this coexistence. This study aimed to evaluate the association between RA and subsequent gout risk in South Korea, considering the serostatus (seropositive RA [SPRA], seronegative RA [SNRA]) and type of biologic/targeted synthetic disease-modifying anti-rheumatic drugs (b/tsDMARDs). This nationwide, population-based cohort study analyzed 34,356 patients newly diagnosed with RA between 2010 and 2017 and 103,068 matched non-RA participants (1:3 ratio based on age and sex). The incident gout was defined according to the claims database diagnostic code for gout. RA patients had a 2.7-fold higher risk of developing gout than non-RA participants (95% confidence interval [CI]: 2.63-2.80). Patie

SUBMITTER: Kang S 

PROVIDER: S-EPMC12290109 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature