Left Main Spontaneous Coronary Artery Dissection: Clinical Features, Management, and Outcomes.

ABSTRACT:

Background

Spontaneous coronary artery dissection (SCAD) is an uncommon cause of acute myocardial infarction (MI) and is associated with substantial adverse events. SCAD involving the left main coronary artery (LM) is a rare but potentially life-threatening condition. Currently, minimal data on LM SCAD have been reported.

Objectives

The aim of this study was to investigate clinical features, contemporary management, and clinical outcomes of patients with LM SCAD.

Methods

A systematic review and pooled analysis of published case reports was conducted using "left main" and "dissection" as keywords. The authors screened 1,106 papers in MEDLINE and Embase published between 1990 and 2023.

Results

The final analysis included 132 patients (mean age 40 ± 11 years, 80%

SUBMITTER: Morosato M 

PROVIDER: S-EPMC12290918 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature