Cumulative environmental exposures and metabolic syndrome: A study of heavy metals and volatile organic compounds.

ABSTRACT:

Background

Metabolic Syndrome (MetS), a condition affecting over one-third of the U.S. population, heightens the risk of cardiovascular disease, Type 2 diabetes, and premature mortality. While individual links between heavy metals (HM), volatile organic compounds (VOC), and MetS have been established, the impact when these environmental toxins are combined remains unclear and unexplored. This study investigates how simultaneous exposure to HMs and VOCs influences the risk of MetS.

Methods

Weighted Quantile Sum regression and Bayesian kernel Machine Regression were performed on data from 6603 participants in the National Health and Nutrition Examination Survey (2011-2020) to determine the impact of HMs and VOCs detected in urine on MetS. Further analyses were performed for in

SUBMITTER: Scardino B 

PROVIDER: S-EPMC12291170 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature