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Left atrium phasic function decreases in adult patients with repaired tetralogy of fallot: a case-control study.


ABSTRACT:

Background

Although the left atrium (LA) plays a key role in diastolic function, LA dysfunction in patients with repaired tetralogy of Fallot (rTOF) remains unclear. Recently, LA strains assessed using a speckle tracking system have been used as novel sensitive indicators of LA function. Therefore, we aimed to evaluate LA function and investigate changes with age in patients with rTOF using speckle-tracking echocardiography.

Methods

We analyzed three age-based subgroups of patients with rTOF (T1, T2, T3) and their corresponding healthy control groups (C1, C2, C3) to assess phasic left atrial function: T1 and C1 (3-9 years [children]), T2 and C2 (10-19 years [adolescents and young adults]), and T3 and C3 (20-44 years [adults]). LA strain was assessed by two-dimensional speckl

SUBMITTER: Sato K 

PROVIDER: S-EPMC12291484 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature