Levels of Zinc, Iron, and Copper in the Aqueous Humor of Patients with Primary Glaucoma.

ABSTRACT:

Background

This case-control study evaluated the concentrations of zinc (Zn), iron (Fe), and copper (Cu) in the aqueous humor (AH) of patients with primary glaucoma, and their relationships with clinical factors.

Methods

This study enrolled 100 patients with primary glaucoma and categorized them into subtypes: acute angle-closure crisis (AACC), primary angle-closure glaucoma (PACG), and primary open-angle glaucoma (POAG). A total of 67 patients with senile cataract were enrolled as controls. Their AH samples and clinical information were obtained.

Results

In primary glaucoma, Zn, Fe, and Cu concentrations increased, especially in AACC group; Zn, Fe, and Cu were positively correlated mutually; and decreased Zn/Fe and increased Fe/Cu were observed. The number of quadran

SUBMITTER: Li Y 

PROVIDER: S-EPMC12292386 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature