Genetic Diversity, Population Structure, and Historical Gene Flow Patterns of Nine Indigenous Greek Sheep Breeds.

ABSTRACT: Ιn this study, we evaluated the genetic resources of nine Greek sheep breeds. The genotyping data of 292 animals were acquired from Illumina's OvineSNP50 Genotyping BeadChip. The genetic diversity and inbreeding levels were evaluated using the observed and expected heterozygosity indices, the F_IS inbreeding coefficient, and runs of homozygosity (ROH). The genetic differentiation of breeds was assessed using the F_ST index, whereas their population structure was analyzed using admixture and principal components analysis (PCA). Historical recombination patterns and genetic drift were evaluated based on linkage disequilibrium, effective population sizes, and gene flow analysis to reveal migration patterns. PCA revealed distinct clusters mostly separating mountainous, insu

SUBMITTER: Michailidou S 

PROVIDER: S-EPMC12292511 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature