Enhanced Visualization of Erythrocytes Through Photoluminescence Using NaYbF₄:Yb³⁺,Er³⁺ Nanoparticles.

ABSTRACT: Rare-earth nanoparticles (RE-NPs), particularly NaYF₄:Yb³⁺,Er³⁺, have emerged as a promising class of photoluminescent probes for bioimaging and sensing applications. These nanomaterials are characterized by their ability to absorb low-energy photons and emit higher-energy photons through an upconversion luminescence process. This process can be triggered by continuous-wave (CW) light excitation, providing a unique optical feature that is not exhibited by native biomolecules. However, the application of upconversion nanoparticles (UCNPs) in bioimaging requires systematic optimization to maximize the signal and ensure biological compatibility. In this work, we synthesized hexagonal-phase UCNPs (average diameter: 29 ± 3 nm) coated with polyacrylic acid (PAA)

SUBMITTER: Torres-Vera V 

PROVIDER: S-EPMC12292841 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature