Genome-Wide Analysis of Oxidosqualene Cyclase Genes in <i>Artemisia annua</i>: Evolution, Expression, and Potential Roles in Triterpenoid Biosynthesis.

ABSTRACT: Plant triterpenoids are structurally diverse specialized metabolites with significant ecological, medicinal, and agricultural importance. Oxidosqualene cyclases (OSCs) catalyze the crucial cyclization step in triterpenoid biosynthesis, generating the fundamental carbon skeletons that determine their structural diversity and biological functions. Genome-wide identification of OSC genes was performed using bioinformatics tools, including HMMER and BLASTP, followed by phylogenetic analysis, gene structure analysis, conserved domain and motifs identification, cis-regulatory element prediction, protein-protein interaction analysis, and expression profiling using publicly available transcriptome data from UV-B treated A. annua six-week-old seedlings. We identified 24 AaOSC genes, classifi

SUBMITTER: Guo C 

PROVIDER: S-EPMC12293385 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature